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Frenagial (Brand name: Anacin)

  • €0.36
  • Brand name: Anacin
  • Disponibilidad: En stock
  • Ingrediente activo: aspirin
Frenagial es un analgésico indicado para el alivio temporal de dolores menores. Frenagial es un salicilato combinación y estimulante. Frenagial bloquea los procesos químicos diferentes en el cuerpo que causan dolor, inflamación y fiebre. Reduce también la tendencia de la coagulación de la sangre.
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525 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €0.46 €27.43
90 píldoras €0.42 €41.14 €37.68
120 píldoras €0.40 €54.85 €47.95
180 píldoras €0.38 €82.28 €68.46
270 píldoras €0.37 €123.42 €99.22
360 píldoras €0.36 €164.56 €130.01


Frenagial is used for treating pain including, headache, muscle aches, sprains, tooth extraction and toothache, menstrual cramps, arthritis and rheumatism, and pain and fever of the common cold. It may also be used for other conditions as determined by your doctor.


Use Frenagial as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Frenagial by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. Taking it with food may not decrease the risk of stomach or bowel problems (eg, bleeding, ulcers) that may occur while taking Frenagial.

Take Frenagial with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Frenagial.

Use Frenagial exactly as directed on the package, unless instructed differently by your doctor. If you are taking Frenagial without a prescription, follow any warnings and precautions on the label.

If you miss a dose of Frenagial and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Frenagial.


Store Frenagial at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Frenagial out of the reach of children and away from pets.


Frenagial may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Frenagial with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate). This includes any medicines that contain caffeine.

Frenagial has aspirin in it. Before you start any new medicine, check the label to see if it has aspirin in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Talk to your doctor before you take Frenagial or other pain relievers/fever reducers if you drink more than 3 drinks with alcohol per day. Serious stomach ulcers or bleeding can occur with the use of Frenagial. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Frenagial with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.

Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Taking more than the recommended dose or taking Frenagial regularly may be habit-forming.

Frenagial may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.

Aspirin has been linked to a serious illness called Reye syndrome. Do not give Frenagial to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.

Diabetes patients - Frenagial may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

If Frenagial has a strong vinegar-like smell upon opening, do not use. It means the medicine is breaking down. Throw the bottle away safely and out of the reach of children; contact your pharmacist and replace.

Tell your doctor or dentist that you take Frenagial before you receive any medical or dental care, emergency care, or surgery.

Do not take Frenagial for at least 7 days after any surgery unless directed by your health care provider.

Do not take Frenagial for more than 10 days for pain or for more than 3 days for fever unless directed to do so by your health care provider.

Different brands of Frenagial may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.




Do NOT use Frenagial if:

  • you are allergic to any ingredient in Frenagial
  • you are a child or teenager with influenza (flu) or chickenpox
  • you have bleeding problems such as hemophilia, von Willebrand disease, or low blood platelets, or you have active severe bleeding
  • you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to aspirin, tartrazine, or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, naproxen, celecoxib)
  • you are taking anticoagulants (eg, heparin, warfarin) or methotrexate

Before using Frenagial:

Some medical conditions may interact with Frenagial. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have alcoholism or if you consume 3 or more alcohol-containing drinks every day
  • if you have asthma, bleeding or clotting problems, growths in the nose (nasal polyps), kidney or liver problems, stomach or intestinal problems (eg, ulcer, inflammation), heart problems, heartburn, upset stomach, stomach pain, hives, influenza (flu) or chickenpox, or vitamin K deficiency
  • if you have anxiety, trouble sleeping, or heart problems
  • if you are a child with a stroke, a weakened blood vessel (cerebral aneurysm) or bleeding in the brain, rheumatic disease (eg, rheumatoid arthritis), or Kawasaki syndrome (a rare inflammation causing heart problems in children) 

Some MEDICINES MAY INTERACT with Frenagial. Tell your health care provider if you are taking any other medicines.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Frenagial while you are pregnant. Frenagial is not recommended during the last 3 months (third trimester) of pregnancy because it may cause harm to the fetus. Frenagial is found in breast milk. If you are or will be breast-feeding while you use Frenagial, check with your doctor. Discuss any possible risks to your baby.


All medicines may cause side effects, but many people have no, or minor, side effects. Frenagial's side effects may include dizziness, heartburn, irritability, nausea, nervousness, rashes, hives, bloody stools, drowsiness, hearing loss, ringing in the ears, and trouble sleeping.

Check with your doctor if any of the listed above most COMMON side effects persist or become bothersome.

Seek medical attention right away if any of these SEVERE side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; diarrhea; drowsiness; hearing loss; ringing in the ears; severe or persistent dizziness; severe or persistent stomach pain or heartburn; shakiness; trouble sleeping; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Incidence Not Known

  • Abdominal or stomach pain, cramping, or burning
  • black, tarry stools
  • bloody or cloudy urine
  • change in consciousness
  • chest pain or discomfort
  • confusion
  • constipation
  • convulsions, severe or continuing
  • dark urine
  • decreased frequency or amount of urine
  • diarrhea
  • difficult breathing
  • drowsiness
  • fainting
  • fast breathing
  • feeling that something terrible will happen
  • fever
  • general tiredness and weakness
  • greatly decreased frequency of urination or amount of urine
  • headache
  • heartburn
  • increased thirst
  • indigestion
  • irregular heartbeat
  • light-colored stools
  • loss of appetite
  • loss of consciousness
  • lower back or side pain
  • muscle cramping and weakness
  • muscle tremors
  • nausea or vomiting
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • panic
  • rapid, deep breathing
  • restlessness
  • seizures
  • skin rash
  • stomach cramps
  • swelling of the face, fingers, or lower legs
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • upper right abdominal or stomach
  • vomiting of blood or material that looks like coffee grounds
  • weakness or heaviness of the legs
  • weight gain
  • yellow eyes and skin
  • Acid or sour stomach
  • anxiety
  • belching
  • dizziness
  • dry mouth
  • hyperventilation
  • irritability
  • shaking
  • stomach discomfort, upset, or pain
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Type Small Molecule
Accession Number DB00945  (APRD00264, EXPT00475)
Groups Approved, Vet approved
  • 2-Acetoxybenzenecarboxylic acid
  • 2-Acetoxybenzoic acid
  • Acetylsalicylate
  • Acetylsalicylsäure
  • acide 2-(acétyloxy)benzoïque
  • acide acétylsalicylique
  • ácido acetilsalicílico
  • Acidum acetylsalicylicum
  • ASA
  • Aspirin
  • Azetylsalizylsäure
  • o-acetoxybenzoic acid
  • O-acetylsalicylic acid
  • o-carboxyphenyl acetate
  • Polopiryna
  • salicylic acid acetate
CAS number 50-78-2
Weight Average: 180.1574
Monoisotopic: 180.042258744
Chemical Formula C9H8O4
2-(acetyloxy)benzoic acid
Protein binding

High (99.5%) to albumin. Decreases as plasma salicylate concentration increases, with reduced plasma albumin concentration or renal dysfunction, and during pregnancy.


Oral, mouse: LD50 = 250 mg/kg; Oral, rabbit: LD50 = 1010 mg/kg; Oral, rat: LD50 = 200 mg/kg. Effects of overdose include: tinnitus, abdominal pain, hypokalemia, hypoglycemia, pyrexia, hyperventilation, dysrhythmia, hypotension, hallucination, renal failure, confusion, seizure, coma, and death.

Half life

The plasma half-life is approximately 15 minutes; that for salicylate lengthens as the dose increases: doses of 300 to 650 mg have a half-life of 3.1 to 3.2 hours; with doses of 1 gram, the half-life is increased to 5 hours and with 2 grams it is increased to about 9 hours.

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