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Stigmicarpin (Brand name: Nimotop)

  • €0.79
  • Brand name: Nimotop
  • Disponibilidad: En stock
  • Ingrediente activo: Nimodipine
Stigmicarpin (Nimodipine) es utilizado para mejorar los síntomas causados ​​por espasmos, como resultado de la hemorragia cerebral (ruptura de vasos sanguíneos).
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30 mg
Nombre del producto Por píldora Por paquete  
30 tapas €1.12 €33.46
60 tapas €0.94 €66.91 €56.33
90 tapas €0.88 €100.37 €79.20
120 tapas €0.85 €133.83 €102.07
180 tapas €0.82 €200.74 €147.81
270 tapas €0.80 €301.11 €216.44
360 tapas €0.79 €401.48 €285.07

INDICATIONS

Stigmicarpin (Nimodipine) is in a group of drugs called calcium channel blockers. Nimodipine relaxes (widens) blood vessels and improves blood flow.

Nimodipine is used to prevent brain damage caused by reduced blood flow to the brain resulting from aneurysm (AN-yor-iz-m), a dilated or ruptured blood vessel in the brain.

Nimodipine may also be used for purposes other than those listed here.

INSTRUCTIONS

Take nimodipine exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor.

Nimodipine gel capsules are to be taken by mouth only. The medicine in the capsule should never be placed into a needle and syringe and injected into a vein. If the person taking nimodipine cannot swallow the capsule, use a needle to make a hole in each end of the capsule, and squeeze the medicine out into an oral syringe. The syringe can then be used to give the medicine through a nasogastric (through the nose and into the stomach) tube.
If you are able to swallow capsules, take nimodipine on an empty stomach, one hour before or two hours after meals. Take each dose with a full glass of water.

It is important to take nimodipine regularly to get the most benefit.
Do not stop taking nimodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

To be sure this medication is helping your condition, your blood pressure will need to be tested on a regular basis. Your liver function may also need to be tested. It is important that you not miss any scheduled visits to your doctor.

DOSAGE

Take the medicine as prescribed by your doctor.

STORAGE

Store nimodipine at room temperature away from moisture and heat.

MORE INFO:

Active ingredient: Nimodipine

Stigmicarpin (nimodipine) belongs to the class of pharmacological agents known as calcium channel blockers.

SAFETY INFORMATION

Before taking nimodipine, tell your doctor if you have liver disease, low blood pressure, high blood pressure (hypertension) for which you take medicine, or a history of heart problems such as a slow heart rate, congestive heart failure, or heart attack.

Nimodipine gel capsules are to be taken by mouth only. The medicine in the capsule should never be placed into a needle and syringe and injected into a vein. If the person taking nimodipine cannot swallow the capsule, use a needle to make a hole in each end of the capsule, and squeeze the medicine out into an oral syringe. The syringe can then be used to give the medicine through a nasogastric (through the nose and into the stomach) tube.

If you are able to swallow capsules, take nimodipine on an empty stomach, one hour before or two hours after meals. Avoid drinking alcohol while you are taking nimodipine. Alcohol and nimodipine may cause low blood pressure, drowsiness, or dizziness. Do not stop taking nimodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known if nimodipine passes into breast milk or if it could harm a nursing infant. Do not take nimodipine without telling your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to have side effects from nimodipine. Your doctor may prescribe a lower dose of this medication.

SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using nimodipine and call your doctor at once if you have any of these serious side effects:

unusually fast or slow heartbeats;

fainting or severe dizziness;

easy bruising or bleeding, unusual weakness;

swelling in your legs or ankles.

Other, less serious side effects may be more likely. Continue taking nimotop and talk to your doctor if you have any of these less serious side effects:

mild dizziness;

flushing (redness, warmth, or tingling feeling);

headache;

nausea, constipation; or

sweating.

Side effects other than those listed here may also occur.

Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Less Common

  • Blurred vision
  • chest pain or discomfort
  • confusion
  • difficult or labored breathing
  • fast, pounding, or irregular heartbeat or pulse
  • lightheadedness, dizziness, or fainting
  • shortness of breath
  • slow or irregular heartbeat
  • sweating
  • swelling
  • tightness in the chest
  • unusual tiredness or weakness
  • Abdominal or stomach cramps, discomfort, or pain
  • back pain
  • blemishes on the skin
  • constipation
  • diarrhea
  • discouragement
  • feeling sad or empty
  • headache
  • indigestion
  • irritability
  • lack or loss of appetite
  • loss of interest or pleasure
  • muscle pain
  • nausea or vomiting
  • pimples
  • rash
  • swollen mouth and tongue
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • unpleasant taste
  • urge to have bowel movement
Type Small Molecule
Accession Number DB00393  (APRD00612)
Groups Approved, Investigational
Synonyms
  • 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ester
  • isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  • isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
  • Nimodipino
  • Nimodipinum
UNII 57WA9QZ5WH
CAS number 66085-59-4
Weight Average: 418.4403
Monoisotopic: 418.174001196
Chemical Formula C21H26N2O7
InChI
InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
IUPAC Name
3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Protein binding

95% bound to plasma protein

Toxicity

Symptoms of overdosage would be expected to be related to cardiovascular effects such as excessive peripheral vasodilation with marked systemic hypotension.

Half life

1.7-9 hours

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