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Sulamine (Brand name: Unisom)

  • €0.54
  • Brand name: Unisom
  • Disponibilidad: En stock
  • Ingrediente activo: Diphenhydramine
Sulamine es utilizado para tratar el insomnio ocasional y reduce la dificultad de dormirse.
Otros nombres de Sulamine (Brand name: Unisom): Sominex   Benadryl  
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25 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €0.76 €22.80
60 píldoras €0.64 €45.60 €38.38
90 píldoras €0.60 €68.40 €53.97
120 píldoras €0.58 €91.19 €69.56
180 píldoras €0.56 €136.79 €100.73
270 píldoras €0.55 €205.19 €147.49
360 píldoras €0.54 €273.58 €194.25

Drug Name

Sulamine (Doxylamine) 

Drug Uses

Sulamine as a single drug (not part of a combination) is used as a short-term treatment for sleep problems (insomnia).

How to use

Take this medicine with food or milk if it upsets your stomach.

Drug Class and Mechanism

Sulamine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. 

Missed Dose

If you miss a dose, take it as soon as you remember. It is better to take Sulamine only when you can devote several hours to sleep. If it is almost your normal waking hour, skip the missed dose and wait until you are ready for bed again. Do not take extra medicine to make up the missed dose. 

Storage

Store Sulamine at room temperature away from moisture and heat.

Warnings/Precautions

Before using Sulamine, tell your doctor if you have glaucoma, kidney disease, an enlarged prostate, problems with urination, a stomach ulcer or obstruction, or a chronic lung disease such as bronchitis or emphysema.

Possible Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects: 

Dizziness; drowsiness; dry mouth, throat, and nose; thickening of mucus in nose or throat. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; decreased alertness; excitability; fast heartbeat; hallucinations; tightness or pounding in the chest; tremor; wheezing.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; decreased alertness; excitability; fast heartbeat; hallucinations; tightness or pounding in the chest; tremor; wheezing.

More Information

Cold or allergy medicine, narcotic pain medicine, other sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by Sulamine. Tell your doctor if you need to use any of these other medicines while you are taking Sulamine.

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Type Small Molecule
Accession Number DB01075  (APRD00587, DB06975)
Groups Approved, Investigational
Synonyms
  • 2-(Benzhydryloxy)-N,N-dimethylethylamine
  • 2-diphenylmethoxy-N,N-demthylethanamine
  • alpha-(2-Dimethylaminoethoxy)diphenylmethane
  • beta-Dimethylaminoethanol diphenylmethyl ether
  • beta-Dimethylaminoethyl benzhydryl ether
  • Difenhidramina
  • Diphenhydraminum
  • N-(2-(Diphenylmethoxy)ethyl)-N,N-dimethylamine
  • O-benzhydryldimethylaminoethanol
  • β-dimethylaminoethyl benzhydryl ether
UNII 8GTS82S83M
CAS number 58-73-1
Weight Average: 255.3547
Monoisotopic: 255.162314299
Chemical Formula C17H21NO
InChI
InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
IUPAC Name
[2-(diphenylmethoxy)ethyl]dimethylamine
Protein binding

98 to 99%

Toxicity

LD50=500 mg/kg (orally in rats). Considerable overdosage can lead to myocardial infarction (heart attack), serious ventricular dysrhythmias, coma and death.

Half life

1-4 hours

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