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Sandoz Enalapril (Brand name: Vasotec)

  • €0.42
  • Brand name: Vasotec
  • Disponibilidad: En stock
  • Ingrediente activo: Enalapril
Sandoz Enalapril es usado para tratar la presión arterial alta, insuficiencia cardíaca y otros problemas cardíacos.
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10 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €0.68 €40.71
90 píldoras €0.60 €61.07 €54.23
120 píldoras €0.56 €81.43 €67.75
180 píldoras €0.53 €122.14 €94.78
270 píldoras €0.50 €183.22 €135.33
360 píldoras €0.49 €244.29 €175.87
5 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €0.60 €36.30
90 píldoras €0.53 €54.45 €47.91
120 píldoras €0.50 €72.60 €59.53
180 píldoras €0.46 €108.90 €82.76
270 píldoras €0.44 €163.35 €117.60
360 píldoras €0.42 €217.79 €152.44

INDICATIONS

Sandoz Enalapril is used for treating high blood pressure, heart failure, and other heart problems. It may be used alone or with other medicines. Sandoz Enalapril is an angiotensin-converting enzyme (ACE) inhibitor. It works by helping to relax blood vessels. This helps to lower blood pressure.

INSTRUCTIONS

Use Sandoz Enalapril as directed by your doctor.

  • Take Sandoz Enalapril by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • If you miss a dose of Sandoz Enalapril, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sandoz Enalapril.

STORAGE

Store Sandoz Enalapril at room temperature below 86 degrees (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Sandoz Enalapril out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Enalapril maleate.

SAFETY INFORMATION

Do NOT use Sandoz Enalapril if:

  • you are allergic to any ingredient in Sandoz Enalapril or similar medicines (eg, captopril, lisinopril)
  • you are pregnant
  • you are taking dextran sulfate or a potassium-sparing diuretic (eg, amiloride).

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Sandoz Enalapril. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have or have ever had liver or kidney problems or kidney transplantation
  • if you are receiving dialysis
  • if you have bone marrow suppression, low blood counts, low blood sodium, high blood potassium, the blood disease porphyria, giant hives, lupus, scleroderma, or a collagen vascular disease
  • if you have narrowing or hardening of the arteries of the brain or heart, chest pain, or discomfort known as angina.

Some medicines may interact with Sandoz Enalapril. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Diuretics (eg, furosemide, hydrochlorothiazide) because excessive decreases in blood pressure may occur, which may cause dizziness, especially upon standing, or fainting
  • Dextran sulfate because it may increase the risk of allergic reaction (eg, rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue) and lightheadedness upon standing
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, aspirin, indomethacin) because they may decrease Sandoz Enalapril's effectiveness and the risk of kidney damage may be increased
  • Oral diabetes medicine (eg, glyburide) because side effects, including a low blood sugar level (eg, dizziness, headache, hunger, shakiness or weakness, sweating), may be increased by Sandoz Enalapril
  • Lithium or thiopurines (eg, azathioprine) because the risk of serious side effects may be increased by Sandoz Enalapril
  • Certain gold-containing medicines (eg, sodium aurothiomalate) because flushing, nausea, vomiting, and low blood pressure may occur
  • Potassium-sparing diuretics (eg, amiloride) or potassium supplements may cause high blood potassium levels (eg, abnormal skin sensations of the arms and legs, confusion, heaviness of the limbs, listlessness, slow or irregular heartbeat, stopping of the heart) when used with Sandoz Enalapril.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sandoz Enalapril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Sandoz Enalapril may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Sandoz Enalapril with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Check with your doctor before you use a salt substitute or a product that has potassium in it.
  • If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel 'normal.' Tell your doctor if you develop any new symptoms.
  • Sandoz Enalapril may not work as well in black patients. They may also be at greater risk of side effects. Contact your doctor if your symptoms do not improve or if they become worse.
  • Sandoz Enalapril may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Sandoz Enalapril. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Tell your doctor or dentist that you take Sandoz Enalapril before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use Sandoz Enalapril. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Sandoz Enalapril should not be used in newborns; safety and effectiveness in these children have not been confirmed.
  • Pregnancy and breast-feeding: Sandoz Enalapril may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. Sandoz Enalapril is found in breast milk. If you are or will be breast-feeding while you use Sandoz Enalapril, check with your doctor. Discuss any possible risks to your baby.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; dizziness or lightheadedness when sitting up or standing; headache; nausea; persistent, dry cough; tiredness; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; hoarseness; infection (eg, fever, sore throat); irregular or slow heartbeat; unusual stomach pain; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

More Common

  • Blurred vision
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • sweating
  • unusual tiredness or weakness
  • Dizziness

Less Common

  • Chest pain
  • cough producing mucus
  • diarrhea
  • difficult or labored breathing
  • fainting
  • fever or chills
  • nausea
  • sneezing
  • sore throat
  • tightness in the chest
  • vomiting
  • Lack or loss of strength
  • rash
Type Small Molecule
Accession Number DB00584  (APRD00510)
Groups Approved, Vet approved
Synonyms
  • (S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
  • (S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
  • 1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
  • Analapril
  • Enalapril
  • Enalaprila
  • Enalaprilum
UNII 69PN84IO1A
CAS number 75847-73-3
Weight Average: 376.4467
Monoisotopic: 376.199822016
Chemical Formula C20H28N2O5
InChI
InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
IUPAC Name
(2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid
Protein binding

50-60% of enalaprilat is bound to plasma proteins

Toxicity

Overdosage may result in marked hypotension and stupor. Most common adverse effects include hypotension, headache, dizziness and fatigue.

Half life

< 2 hours for unchanged enalapril in health individuals, may be increased in those with congestive heart failure (3.4 and 5.8 hours for single 5- and 10-mg doses, respectively). The average terminal half life of enalaprilat is 35-38 hours. The effective half life following multiple doses is 11-14 hours.

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