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Uroxal (Brand name: Ditropan)

  • €1.92
  • Brand name: Ditropan
  • Disponibilidad: En stock
  • Ingrediente activo: Oxybutynin
Uroxal es utilizado para aliviar los síntomas de problemas de la vejiga (urgencia urinaria, frecuencia o escurrimiento, la pérdida de control de la vejiga, y evacuación urinaria dolorosa) en ciertos pacientes.
Otros nombres de Uroxal (Brand name: Ditropan): Oxytrol  
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5 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €4.95 €148.45
60 píldoras €3.60 €296.90 €215.93
90 píldoras €3.15 €445.35 €283.41
120 píldoras €2.92 €593.80 €350.88
180 píldoras €2.70 €890.71 €485.84
270 píldoras €2.55 €1,336.06 €688.27
360 píldoras €2.47 €1,781.41 €890.69
2.5 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €4.09 €245.60
90 píldoras €3.23 €368.40 €290.30
120 píldoras €2.79 €491.20 €335.00
180 píldoras €2.36 €736.81 €424.40
270 píldoras €2.07 €1,105.21 €558.49
360 píldoras €1.92 €1,473.61 €692.60

INDICATIONS

Uroxal is used for relieving symptoms of bladder problems (urinary urgency, frequency, or leakage; loss of bladder control; and painful urination) in certain patients. Uroxal is an anticholinergic. It works by relaxing muscles in the bladder.

INSTRUCTIONS 

Use Uroxal as directed by your doctor.

  • Take Uroxal by mouth with or without food.
  • Take Uroxal on a regular schedule to get the most benefit from it. Taking Uroxal at the same time each day will help you remember to take it.
  • Continue to take Uroxal event if you feel well. Do not miss any dose.
  • If you miss a dose of Uroxal, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Uroxal.

STORAGE

Store Uroxal at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tight container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Uroxal out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Oxybutynin chloride.

SAFETY INFORMATION

Do NOT use Uroxal if:

  • you are allergic to any ingredient in Uroxal
  • you have bladder blockage or are unable to urinate
  • you have certain stomach or bowel problems (eg, blockage, decreased muscle movement) or tightening of the esophagus
  • you have uncontrolled narrow-angle glaucoma
  • you have heart problems caused by severe bleeding.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Uroxal. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have trouble urinating or have very poor health
  • if you have a history of heart problems (eg, heart failure, fast or irregular heartbeat), high blood pressure, nervous system problems, esophagus problems (eg, reflux disease, inflammation), stomach or bowel problems (eg, colitis, inflammation), or hiatal hernia
  • if you have a history of liver or kidney problems, myasthenia gravis, an enlarged prostate, an overactive thyroid, or glaucoma, or if you are at risk for glaucoma.

Some medicines may interact with Uroxal. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticholinergics (eg, scopolamine), azole antifungals (eg, ketoconazole), or macrolide antibiotics (eg, erythromycin) because they may increase the risk of Uroxal's side effects
  • Bisphosphonates (eg, alendronate) because the risk of irritation of the esophagus may be increased
  • Phenothiazines (eg, chlorpromazine) because their effectiveness may be decreased by Uroxal and they may increase the risk of Uroxal's side effects.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Uroxal may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Uroxal may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Uroxal with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Uroxal; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Uroxal may cause decreased sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur. Contact your doctor if you have been exposed to high temperatures and you develop fever; flushing; hot, dry skin; severe or persistent headache; dizziness; sudden fatigue; fast heartbeat; seizures; or fainting.
  • Uroxal may cause dry mouth. To help relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Ask your doctor or pharmacist if you have any questions.
  • Use Uroxal with caution in the elderly; they may be more sensitive to its effects.
  • Uroxal should be used with extreme caution in children younger 5 years; safety and effectiveness in these children have not been confirmed.
  • Pregnancy and breast-feeding: It is not known if Uroxal can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Uroxal while you are pregnant. It is not known if Uroxal is found in breast milk. If you are or will be breast-feeding while you use Uroxal, check with your doctor. Discuss any possible risks to your baby.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Blurred vision; constipation; diarrhea; dizziness; drowsiness; dry eyes, nose, skin, or mouth; headache; indigestion; nausea; stomach pain; taste changes; trouble sleeping.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficult or painful urination; fast or irregular heartbeat; fever; hallucinations; mental or mood changes (eg, agitation); seizures; swelling of the hands, ankles, or feet; vision problems.

 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Rare

  • Eye pain
  • skin rash or hives

More Common

  • Acid or sour stomach
  • belching
  • decreased sweating
  • diarrhea
  • difficulty having a bowel movement (stool)
  • drowsiness
  • dryness of the eyes, mouth, nose, or throat
  • heartburn
  • indigestion
  • runny nose
  • stomach discomfort, upset, or pain
Type Small Molecule
Accession Number DB01062  (APRD00427)
Groups Approved, Investigational
Synonyms
  • 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
  • 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat
  • 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
  • Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester
  • Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester
  • Oxibutinina
  • Oxybutynin
  • Oxybutynine
  • Oxybutyninum
UNII K9P6MC7092
CAS number 5633-20-5
Weight Average: 357.4864
Monoisotopic: 357.230393863
Chemical Formula C22H31NO3
InChI
InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3
IUPAC Name
4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate
Protein binding

91%-93%

Toxicity

LD50=1220 mg/kg (Orally in rats, Goldenthal)

Half life

12.4-13.2 hours

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