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Solaban (Brand name: Lamictal)

  • €0.78
  • Brand name: Lamictal
  • Disponibilidad: En stock
  • Ingrediente activo: Lamotrigine
Solaban es utilizado para tratar ciertos tipos de ataques.
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Arvind   Apo-lamotrigine   An Xian   Apo-lamotrigine   Arrow Lamotrigine   Arvind   Aspen Lamotrigine   Solaban  
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200 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €3.44 €103.14
60 píldoras €2.76 €206.28 €165.44
90 píldoras €2.53 €309.41 €227.73
120 píldoras €2.42 €412.55 €290.02
180 píldoras €2.30 €618.83 €414.61
50 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €1.66 €49.93
60 píldoras €1.30 €99.86 €77.96
90 píldoras €1.18 €149.80 €105.98
120 píldoras €1.12 €199.73 €134.01
180 píldoras €1.06 €299.59 €190.05
270 píldoras €1.02 €449.39 €274.14
25 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €1.31 €39.23
60 píldoras €1.02 €78.46 €61.35
90 píldoras €0.93 €117.69 €83.45
120 píldoras €0.88 €156.92 €105.57
180 píldoras €0.83 €235.39 €149.80
270 píldoras €0.80 €353.08 €216.12
360 píldoras €0.78 €470.77 €282.45
100 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €1.76 €52.68
60 píldoras €1.37 €105.36 €82.25
90 píldoras €1.24 €158.04 €111.81
120 píldoras €1.18 €210.73 €141.39
180 píldoras €1.11 €316.09 €200.52
270 píldoras €1.07 €474.13 €289.23

INDICATIONS

Solaban is used for treating certain types of seizures. It may be used alone or with other medicines. It may also be used to delay the occurrence of mood problems in certain patients with bipolar disorder. Solaban is an anticonvulsant.

INSTRUCTIONS 

Use Solaban as directed by your doctor.

  • Take Solaban by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Solaban has a bitter taste. Do not crush or chew before swallowing. The tablet may be broken in half if your doctor tells you to do so.
  • Continue to take Solaban even if you feel well. Do not miss any dose.
  • If you miss a dose of Solaban, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Solaban.

STORAGE

Store Solaban at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Solaban out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Lamotrigine.

SAFETY INFORMATION

Do NOT use Solaban if:

  • you are allergic to any ingredient in Solaban.

Some medical conditions may interact with Solaban. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver, kidney, or heart problems; certain blood problems (eg, thalassemia); or if you receive dialysis treatment
  • if you have a skin rash or have ever developed a skin rash from taking Solaban or any other medicines to treat seizures
  • if you have a history of mental or mood problems (eg, depression, suicidal thoughts or attempts).

Some medicines may interact with Solaban. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Carbamazepine because it may decrease Solaban's effectiveness, and the risk of side effects, such as dizziness, double vision, blurred vision, and decreased coordination, may be increased
  • Valproate (eg, valproic acid, divalproex sodium) because it may increase the risk of Solaban's side effects
  • Estrogens, phenobarbital, phenytoin, primidone, rifampin, or succinimides (eg, methsuximide) because they may decrease Solaban's effectiveness
  • Hormonal contraceptives (eg, birth control pills) because the effectiveness of both medicines may be decreased.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Solaban may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Solaban may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Solaban with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Do not suddenly stop taking Solaban or change your dose without checking with your doctor. Doing so may increase seizure frequency. If you need to stop taking Solaban, your dose should be gradually reduced over a period of at least 2 weeks.
  • If you stop taking Solaban for any reason, contact your doctor right away. Do not start taking it again unless your doctor tells you to. Discuss any questions or concerns with your doctor.
  • If you develop new or worsening seizures, contact your doctor right away.
  • Patients who take Solaban may be at increased risk of suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Patients who have bipolar (manic-depressive) illness may also have an increased risk of suicidal thoughts or actions. Watch patients who take Solaban closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
  • Hormonal birth control (eg, birth control pills) may change the amount of Solaban in your blood. Talk to your doctor before you start or stop taking hormonal birth control while you are taking Solaban. Women who take hormonal birth control may be at greater risk of side effects during the week of inactive pills in their pack. Contact your doctor if side effects, such as dizziness, decreased coordination, or double vision, occur.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Solaban. Check with your doctor if you have questions about how Solaban might affect your hormonal birth control. Contact your doctor right away if you notice any unusual vaginal bleeding or spotting. If you wish to avoid pregnancy, talk with your doctor about the use of effective birth control methods.
  • Tell your doctor or dentist that you take Solaban before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including complete blood cell counts, may be performed while you use Solaban. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Different medicines may look like or have names similar to Solaban. Always check your medicine to make sure it is correct. If you notice any change in the appearance of your medicine (eg, shape, color, size, wording), check with your pharmacist.
  • Caution is advised when using Solaban in children; they may be more sensitive to its effects, especially the risk of serious rash.
  • Increased sensitivity to the sun has been reported in some children taking Solaban. Use a sunscreen or protective clothing if your child will be exposed to the sun. Discuss any questions or concerns with your doctor.
  • Solaban should be used with extreme caution in children younger 18 years with bipolar disorder; safety and effectiveness in these children have not been confirmed.
  • Solaban should be used with extreme caution in children younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • Pregnancy and breast-feeding: Solaban may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Solaban while you are pregnant. Solaban is found in breast milk. Do not breastfeed while taking Solaban.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Blurred or double vision; constipation; decreased coordination; diarrhea; dizziness; drowsiness; headache; nausea; painful menstrual periods; runny or stuffy nose; stomach upset or pain; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); absent menstrual period or other menstrual changes; calf pain or tenderness; chest pain; dark urine; difficult or painful urination; fast or irregular heartbeat; fever, chills, or persistent sore throat; new or worsening mental or mood changes (eg, anxiety, depression, restlessness, irritability, panic attacks, behavior changes, suicidal thoughts or attempts); new or worsening seizures; pale stools; reddened, blistered, swollen, or peeling skin; severe muscle pain or tenderness; severe or persistent stomach pain; shortness of breath; sores in the mouth or around the eyes; swelling of the hands, ankles, or feet; swollen lymph glands; tremor; unusual bruising or bleeding; unusual weakness or tiredness; vaginal itching or discharge; vision changes; yellowing of the eyes or skin.

 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. 

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Rare

  • Blistering, peeling, or loosening of the skin
  • chills
  • dark-colored urine
  • fever
  • flu-like symptoms
  • itching
  • memory loss
  • muscle cramps, pain, or weakness
  • red or irritated eyes
  • small red or purple spots on the skin
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of the face, mouth, hands, or feet
  • swollen lymph nodes
  • trouble with breathing
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • yellow eyes or skin

More Common

  • Blurred vision
  • changes in vision
  • clumsiness or unsteadiness
  • double vision
  • poor coordination
  • skin rash
  • Dizziness
  • drowsiness
  • headache
  • nausea
  • vomiting

Less Common

  • Anxiety
  • chest pain
  • confusion
  • continuous, uncontrolled back and forth or rolling eye movements
  • depression
  • increase in seizures
  • infection
  • irritability
  • Diarrhea
  • indigestion
  • loss of strength
  • menstrual pain
  • pain
  • runny nose
  • trembling or shaking
  • trouble with sleeping
  • unusual weight loss

Incidence Not Known

  • Back, leg, or stomach pains
  • bleeding gums
  • bloating
  • blood in the urine
  • bloody, black or tarry stools
  • bluish lips or skin
  • bruising
  • constipation
  • cough or hoarseness
  • coughing or vomiting blood
  • difficulty with breathing
  • difficulty with swallowing
  • fainting
  • fast heartbeat
  • general body swelling
  • general feeling of discomfort or illness
  • general feeling of tiredness or weakness
  • heartburn
  • high fever
  • lightheadedness
  • loss of appetite
  • loss of balance control
  • lower back or side pain
  • mask-like face
  • muscle spasms
  • nosebleeds
  • not breathing
  • pain or burning in the throat
  • painful or difficult urination
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pale skin
  • persistent bleeding or oozing from puncture sites, mouth, or nose
  • rapid, shallow breathing
  • redness, soreness, or itching skin
  • shortness of breath
  • shuffling walk
  • slowed movement
  • slurred speech
  • sores, welting, or blisters
  • stiffness of the arms and legs
  • swollen or painful glands
  • tic-like (jerky) movements
  • tightness in the chest
  • unexplained bleeding or bruising
  • wheezing
Type Small Molecule
Accession Number DB00555  (APRD00570)
Groups Approved, Investigational
Synonyms
  • 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
  • Lamotrigina
  • Lamotrigine
  • Lamotriginum
UNII U3H27498KS
CAS number 84057-84-1
Weight Average: 256.091
Monoisotopic: 255.007850663
Chemical Formula C9H7Cl2N5
InChI
InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
IUPAC Name
6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
Protein binding

The fraction of plasma protein is 55% in vitro. Lamotrigine is not expected to undergo clinically significant interactions with other drugs through competition for protein binding sites [Label].

Toxicity

Some fatal cases of overdose involving quantities up to 15 g have been reported. Overdose has resulted in ataxia, nystagmus, increased seizures, decreased level of consciousness, coma, and intraventricular conduction delay. While there is no known antidote for lamotrigine, hospitalization and general supportive care is recommended in case of suspected overdose. If indicated, gastric lavage and emesis may be required with appropriate precautions made to protect the airway. It is uncertain whether hemodialysis is an effective means of removing lamotrigine from the blood [Label].

Oral TDLO in man is 19 mg/kg and oral TDLO (intermittent) in woman is 2 mg/kg/30H [MSDS]. Oral LD50 in mouse and rat is 205 mg/kg and 245 mg/kg, respectively [MSDS]. In animal studies, lamotrigine was not found to be teratogenic. However it decreased fetal folate concentrations in rats, an effect known to be associated with teratogenesis in animals and humans [Label]. There is no evidence of carcinogenic or mutagenic potential for lamotrigine and effect of lamotrigine on human fertility is unknown [Label].

Half life

The mean elimination half life ranges from 12-59 hours. The value is dependent on dosing regimen, concomitant antiepileptic medications, and disease state of the individual.

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  • Bogotá
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  • Bucaramanga
  • Villavicencio
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  • Valledupar
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  • Manizales
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  • Dosquebradas