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Socliden (Brand name: Oxytrol)

  • €0.69
  • Brand name: Oxytrol
  • Disponibilidad: En stock
  • Ingrediente activo: Oxybutynin
Socliden es utilizado para aliviar los síntomas de problemas de la vejiga (urgencia urinaria, frecuencia o pérdida, la pérdida de control de la vejiga, y evacuación urinaria dolorosa) en ciertos pacientes.
Otros nombres de Socliden (Brand name: Oxytrol): Ditropan  
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5 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €1.37 €41.14
60 píldoras €1.18 €82.28 €71.06
90 píldoras €1.12 €123.42 €100.98
120 píldoras €1.09 €164.56 €130.90
180 píldoras €1.06 €246.84 €190.74
270 píldoras €1.04 €370.27 €280.50
360 píldoras €1.03 €493.69 €370.27
2.5 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €0.96 €28.76
60 píldoras €0.81 €57.52 €48.73
90 píldoras €0.76 €86.28 €68.71
120 píldoras €0.74 €115.04 €88.69
180 píldoras €0.71 €172.56 €128.64
270 píldoras €0.70 €258.84 €188.56
360 píldoras €0.69 €345.13 €248.50

INDICATIONS

Socliden (oxybutynin) reduces muscle spasms of the bladder and urinary tract.

Socliden transdermal skin patch is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.

Socliden may also be used for purposes not listed in this medication guide.

INSTRUCTIONS

Use Socliden exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Socliden comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

To use the Socliden patch, open the sealed pouch and remove the protective liner. Apply the transdermal patch to a clean, dry area on your stomach, hip or buttock. Avoid skin that is oily, irritated, or damaged. Avoid placing the patch on a skin area that will be rubbed by a waistband or tight clothing.

Press the Socliden patch onto the skin and press it down firmly with your fingers. Make sure the patch is well sealed around the edges. When properly applied, the patch should stay on while swimming or bathing.

Leave the Socliden patch in place and wear it for 3 to 4 days. You should change the patch twice per week. Each time you apply a new patch, choose a different skin area on your stomach, hip, or buttock. Do not apply a patch to the same skin twice within one week.

Try to change your Socliden patch on the same two days each week (such as every Sunday and Thursday). There is a calendar printed on the package of this medication to help you establish a steady patch-changing schedule.

If the patch falls off, try sticking it back on. If it does not stay on, replace it with a new one and wear it until your next regular patch-changing day. Do not change your schedule, even if you apply a new patch to replace one that has fallen off.

After removing an Socliden patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it.

Use baby oil or mild soap and water to remove any adhesive residue that stays on your skin. Avoid using harsh soaps, alcohol, nail polish remover, or other solvents that could irritate your skin.

The Socliden patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test. Keep the Socliden patch in its sealed pouch until you are ready to use it.  

DOSAGE 

Adults: The usual dose is 5mg two or three times a day. This may be increased to a maximum of 5 mg four times a day to obtain a clinical response provided that the side effects are tolerated.

Elderly (including frail elderly):
The elimination half-life is increased in the elderly. Therefore, a dose of 2.5mg twice a day, particularly if the patient is frail, is likely to be adequate. This dose may be titrated upwards to 5mg two times a day to obtain a clinical response provided the side effects are well tolerated.

Children (under 5 years of age):
Not recommended.

Children (over 5 years of age):
Neurogenic bladder instability: the usual dose is 2.5mg twice a day. This dose may be titrated upwards to 5mg two or three times a day to obtain a clinical response provided the side effects are well tolerated. Nocturnal enuresis: the usual dose is 2.5mg twice a day. This dose may be titrated upwards to 5mg two or three times a day to obtain a clinical response provided the side effects are tolerated. The last dose should be given before bedtime.  

STORAGE

Store this medicine at room temperature in a tightly-closed container, away from heat and light.

MORE INFO:

 Active ingredient: Oxybutynin

SAFETY INFORMATION

Do not use Socliden if you are allergic to oxybutynin, or if you have:

untreated or uncontrolled glaucoma;

a blockage in your digestive tract (stomach or intestines); or

if you have decreased urination or are unable to urinate.

To make sure you can safely use Socliden, tell your doctor if you have any of these other conditions:

glaucoma;

liver disease;

kidney disease;

myasthenia gravis;

an enlarged prostate;

an intestinal disorder, such as ulcerative colitis; or

a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

FDA pregnancy category B. Socliden is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether oxybutynin passes into breast milk or if it could harm a nursing baby. Do not use Socliden without telling your doctor if you are breast-feeding a baby.

Important safety information: 

Before using Socliden, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by oxybutynin.

Tell your doctor about all other medicines you use, especially:

atropine (Donnatal, and others);

belladonna;

dicyclomine (Bentyl);

glycopyrrolate (Robinul);

hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);

mepenzolate (Cantil);

methantheline (Provocholine);

methscopolamine (Pamine);

propantheline (Pro-Banthine);

scopolamine (Transderm-Scop);

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek); or

antifungal medicine such as itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), miconazole (Oravig), or voriconazole (Vfend).

This list is not complete and other drugs may interact with Socliden. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction to Socliden: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Socliden and call your doctor at once if you have a serious side effect such as:

fever with hot, dry skin;

uneven heart rate;

pain or burning when you urinate;

urinating less than usual or not at all; or

severe itching, burning, or blistering that does not clear up within several hours after removing the skin patch.

Less serious Socliden side effects may include:

mild skin itching, burning, redness, or discoloration where a patch was worn;

dizziness, drowsiness, weakness;

dry eyes, blurred vision;

dry mouth;

warmth, tingling, or redness under your skin;

nausea, vomiting, stomach pain;

constipation or diarrhea;

stuffy nose;

back pain;

feeling restless; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Rare

  • Eye pain
  • skin rash or hives

More Common

  • Acid or sour stomach
  • belching
  • decreased sweating
  • diarrhea
  • difficulty having a bowel movement (stool)
  • drowsiness
  • dryness of the eyes, mouth, nose, or throat
  • heartburn
  • indigestion
  • runny nose
  • stomach discomfort, upset, or pain
Type Small Molecule
Accession Number DB01062  (APRD00427)
Groups Approved, Investigational
Synonyms
  • 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
  • 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat
  • 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
  • Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester
  • Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester
  • Oxibutinina
  • Oxybutynin
  • Oxybutynine
  • Oxybutyninum
UNII K9P6MC7092
CAS number 5633-20-5
Weight Average: 357.4864
Monoisotopic: 357.230393863
Chemical Formula C22H31NO3
InChI
InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3
IUPAC Name
4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate
Protein binding

91%-93%

Toxicity

LD50=1220 mg/kg (Orally in rats, Goldenthal)

Half life

12.4-13.2 hours

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