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Setofilm (Brand name: Zofran)

  • €0.28
  • Brand name: Zofran
  • Disponibilidad: En stock
  • Ingrediente activo: Ondansetron
Setofilm es usado para la prevención de náuseas y vómitos asociados con quimioterapia o cirugía.
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8 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €0.98 €29.31
60 píldoras €0.77 €58.62 €46.47
90 píldoras €0.71 €87.94 €63.64
120 píldoras €0.67 €117.25 €80.80
180 píldoras €0.64 €175.87 €115.12
270 píldoras €0.62 €263.81 €166.59
360 píldoras €0.61 €351.74 €218.09
4 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €0.50 €30.04
90 píldoras €0.41 €45.06 €37.13
120 píldoras €0.37 €60.08 €44.22
180 píldoras €0.32 €90.12 €58.39
270 píldoras €0.30 €135.17 €79.67
360 píldoras €0.28 €180.23 €100.93

INDICATIONS

Setofilm is used for preventing nausea and vomiting associated with cancer chemotherapy or surgery. Setofilm is a serotonin 5-HT3 receptor blocker. It works by blocking a chemical thought to be a cause of nausea and vomiting in certain situations (eg, chemotherapy).

INSTRUCTIONS 

Use Setofilm as directed by your doctor.

  • Take Setofilm with a full glass of water.
  • This medicine can be taken with or without food.
  • Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
  • If you miss a dose of Setofilm, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Setofilm.

STORAGE

Store Setofilm at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Setofilm out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Ondansetron.

SAFETY INFORMATION

Do NOT use Setofilm if:

  • you are allergic to any ingredient in Setofilm
  • you are taking apomorphine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Setofilm. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had an allergic reaction to another serotonin 5-HT3 receptor blocker (eg, dolasetron, granisetron)
  • if you have liver problems or a certain type of irregular heartbeat (QT prolongation, long QT syndrome).

Some medicines may interact with Setofilm. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Apomorphine because the risk of its side effects may be increased by Setofilm
  • Antineoplastic agents (eg, cyclophosphamide) because their effectiveness may be decreased by Setofilm.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Setofilm may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Setofilm may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Setofilm with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Setofilm should be used with extreme caution in children younger 4 months; safety and effectiveness in these children have not been confirmed. Certain strengths of Setofilm are not recommended in children. If you have questions about using Setofilm in children, contact your doctor or pharmacist.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Setofilm while you are pregnant. It is not known if Setofilm is found in breast milk. If you are or will be breast-feeding while you use Setofilm, check with your doctor. Discuss any possible risks to your baby.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; headache; tiredness.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; wheezing; unusual hoarseness); chest or jaw pain; fainting; fast, slow, or irregular heartbeat; fever; numbness of an arm or leg, or sudden severe headache or vomiting; seizures; severe or persistent dizziness; skin tingling or numbness; stomach pain; trouble urinating; uncontrolled muscle movements; vision changes or loss.

 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Rare

  • Arm, back, or jaw pain
  • chest pain or discomfort
  • chest tightness or heaviness
  • convulsions
  • cough
  • decreased urine
  • difficulty with breathing
  • difficulty with swallowing
  • dry mouth
  • fast, pounding, or irregular heartbeat or pulse
  • increased thirst
  • loss of appetite
  • loss of bladder control
  • loss of consciousness
  • mood changes
  • muscle pain or cramps
  • nausea or vomiting
  • noisy breathing
  • numbness or tingling in the hands, feet, or lips
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • skin rash, hives, or itching
  • sweating
  • tightness in the chest
  • total body jerking
  • unusual tiredness or weakness
  • wheezing
  • Difficulty with speaking
  • drooling
  • loss of balance control
  • muscle trembling, jerking, or stiffness
  • shuffling walk
  • stiffness of the limbs
  • twisting movements of the body
  • uncontrolled movements, especially of the face, neck, and back

More Common

  • Confusion
  • dizziness
  • fast heartbeat
  • fever
  • headache
  • shortness of breath
  • weakness
  • Anxiety
  • difficulty having a bowel movement (stool)
  • dry mouth
  • general feeling of discomfort or illness
  • hyperventilation
  • irritability
  • restlessness
  • shaking
  • trouble sleeping

Less Common

  • Decrease in the frequency of urination
  • decrease in the urine volume
  • difficulty with passing urine (dribbling)
  • painful urination

Incidence Not Known

  • Blurred vision
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fixed position of the eye
  • heart stops
  • hoarseness
  • inability to move the eyes
  • increased blinking or spasms of the eyelid
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • no breathing
  • no pulse or blood pressure
  • noisy breathing
  • pounding heartbeat
  • slow or irregular breathing
  • sticking out of the tongue
  • sweating
  • trouble with speaking
  • unconscious
  • uncontrolled twisting movements of the neck, trunk, arms, or legs
  • unusual facial expressions
  • Feeling of warmth
  • hiccups
  • redness of the face, neck, arms, and occasionally, upper chest
  • redness of the skin
  • welts
Type Small Molecule
Accession Number DB00904  (APRD00481)
Groups Approved
Synonyms Not Available
UNII 4AF302ESOS
CAS number 99614-02-5
Weight Average: 293.363
Monoisotopic: 293.152812245
Chemical Formula C18H19N3O
InChI
InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3
IUPAC Name
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one
Protein binding

70%-76% (Plasma protein binding)

Toxicity

Low blood pressure and fainting, sudden blindness, severe constipation

Half life

5.7 hours

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