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Shiphnos (Brand name: Dipyridamole)

  • €0.27
  • Brand name: Dipyridamole
  • Disponibilidad: En stock
  • Ingrediente activo:
Shiphnos es utilizado para evaluar la enfermedad coronaria en los pacientes que no pueden ejercer adecuadamente antes de la exploración con talio (exploración cardiaca el flujo de sangre).
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100 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €0.91 €27.44
60 píldoras €0.75 €54.88 €44.70
90 píldoras €0.69 €82.33 €61.97
180 píldoras €0.63 €164.65 €113.75
270 píldoras €0.61 €246.98 €165.56
360 píldoras €0.60 €329.31 €217.34
25 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €0.49 €29.32
90 píldoras €0.40 €43.98 €36.24
120 píldoras €0.36 €58.64 €43.17
180 píldoras €0.32 €87.97 €57.00
270 píldoras €0.29 €131.95 €77.77
360 píldoras €0.27 €175.93 €98.52

INDICATIONS

Shiphnos is used for evaluating coronary artery disease in patients who cannot exercise adequately before thallium imaging (cardiac blood flow scan). Shiphnos is a coronary vasodilator. It works by increasing blood flow to the heart, which mimics an exercise test. It is followed by the thallium test.

INSTRUCTIONS 

Use Shiphnos as directed by your doctor.

  • Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
  • Take Shiphnos with a full glass (8 ounces) of water.
  • Shiphnos is often taken together with other medications to prevent blood clots. To best treat your condition, use all of your medications as directed by your doctor. 
  • To be sure this medication is not causing harmful effects, your doctor may need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.
  • If you miss a dose of Shiphnos, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Ask your health care provider any questions you may have about how to use Shiphnos.

STORAGE

 Store Shiphnos at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not freeze. Keep Shiphnos out of the reach of children and away from pets.

SAFETY INFORMATION

Do NOT use Shiphnos if:

  • you are allergic to any ingredient in Shiphnos.

Some medical conditions may interact with Shiphnos. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have asthma; chest pain (angina); heart disease; heart block; or abnormal, rapid, slow, or irregular heartbeat
  • if you have severe muscle weakness.

Some medicines may interact with Shiphnos. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Theophyllines (eg, aminophylline) because they may decrease Shiphnos's effectiveness
  • Adenosine because the risk of its side effects, including low blood pressure and irregular heartbeat, may be increased by Shiphnos
  • Anticholinesterases (eg, pyridostigmine) because their effectiveness may be decreased by Shiphnos.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Shiphnos may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Shiphnos may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Shiphnos with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Avoid food or drink that has caffeine (eg, coffee, tea, cocoa, cola, chocolate) before you use Shiphnos.
  • Shiphnos should not be used in children; safety and effectiveness in children have not been confirmed.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Shiphnos while you are pregnant. Shiphnos is found in breast milk. Do not breastfeed while taking Shiphnos.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Dizziness; fatigue; flushing; headache; nausea.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; confusion; fast, irregular, or slow heartbeat; one-sided weakness; seizures; slurred speech.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Rare

  • Chest pain
  • gallstones
  • tightness or swelling of neck
  • yellow eyes or skin
  • General discomfort and/or unusual tiredness or weakness
  • hair loss
  • joint pain or swelling
  • muscle pain
  • runny nose
  • sneezing

More Common

  • Abdominal or stomach cramps
  • diarrhea
  • dizziness or lightheadedness

Less Common

  • Flushing
  • headache
  • nausea or vomiting
  • weakness
Type Small Molecule
Accession Number DB00975  (APRD00360)
Groups Approved
Synonyms
  • Cleridium 150
  • Curantyl
  • Dipiridamol
  • Dipyridamine
  • Dipyridamolum
  • Dipyudamine
  • Dypyridamol
  • Persantin
UNII 64ALC7F90C
CAS number 58-32-2
Weight Average: 504.6256
Monoisotopic: 504.317251808
Chemical Formula C24H40N8O4
InChI
InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2
IUPAC Name
2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol
Protein binding

99%

Toxicity

Hypotension, if it occurs, is likely to be of short duration, but a vasopressor drug may be used if necessary. The oral LD50 in rats is greater than 6,000 mg/kg while in the dogs, the oral LD50 is approximately 400 mg/kg. LD50=8.4g/kg (orally in rat)

Half life

40 minutes

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