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Sicadol (Brand name: Ponstel)

  • €0.27
  • Brand name: Ponstel
  • Disponibilidad: En stock
  • Ingrediente activo: mefenamic acid
Sicadol (Mefenamic Acid) es indicado para el tratamiento del dolor.
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250 mg
Nombre del producto Por píldora Por paquete  
90 píldoras €0.41 €37.14
120 píldoras €0.36 €49.52 €43.75
180 píldoras €0.32 €74.28 €56.94
270 píldoras €0.28 €111.42 €76.76
360 píldoras €0.27 €148.56 €96.57
500 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €0.58 €34.58
90 píldoras €0.50 €51.88 €44.61
120 píldoras €0.46 €69.17 €54.64
180 píldoras €0.42 €103.75 €74.70
270 píldoras €0.39 €155.63 €104.79
360 píldoras €0.37 €207.51 €134.88

INDICATIONS 

Sicadol (Mefenamic Acid) is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Mefenamic acid works by reducing hormones that cause inflammation and pain in the body.

Mefenamic acid is used to treat pain or inflammation caused by arthritis. It is also used to treat menstrual pain.

Mefenamic acid may also be used for other purposes not listed in this medication guide.

INSTRUCTIONS  

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

If you take mefenamic acid for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.

DOSAGE 

Take the medicine as directed by your doctor.

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, stomach pain, dizziness, drowsiness, black or bloody stools, coughing up blood, urinating less than usual or not at all, shallow breathing, fainting, or coma.

STORAGE 

Store mefenamic acid at room temperature, away from moisture, heat, and light.

MORE INFO:

Active Ingredient: Mefenamic Acid

SAFETY INFORMATION

This medicine can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

This medicine can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking mefenamic acid. Older adults may have an even greater risk of these serious gastrointestinal side effects.

Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist.

Do not drink alcohol while taking mefenamic acid. Alcohol can increase the risk of stomach bleeding.

Important safety information: 

Tell your doctor if you are taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking any of these drugs with mefenamic acid may cause you to bruise or bleed easily.

Before taking mefenamic acid, tell your doctor if you are taking any of the following drugs:

a blood thinner such as warfarin (Coumadin);

a diuretic (water pill) such as furosemide (Lasix);

cyclosporine (Gengraf, Neoral, Sandimmune);

lithium (Eskalith, Lithobid);

methotrexate (Rheumatrex, Trexall);

steroids (prednisone and others); or

aspirin or NSAIDs (non-steroidal anti-inflammatory drugs) such as diclofenac (Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), meclofenamate (Meclomen), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.

This list is not complete and there may be other drugs that can interact with mefenamic acid. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking mefenamic acid and seek medical attention or call your doctor at once if you have any of these serious side effects:

chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;

black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;

urinating less than usual or not at all;

pain, burning, or bleeding when you urinate;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

bruising, severe tingling, numbness, pain, muscle weakness.

Less serious side effects may include:

upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas;

dizziness, headache, nervousness;

skin itching or rash;

dry mouth;

increased sweating, runny nose;

blurred vision; or

ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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Para no experimentar las reacciones no deseadas y los efectos secundarios hemos de tener en cuenta las contraindicaciones, advertencias y las precauciones. Aun así, algunos pacientes hipersensibles podrían experimentar reacciones negativas de diferente grado que vamos a enumerar. Busque asistencia médica sin hesitar en el momento en que haya notado los siguientes efectos secundarios que enumeraremos más abajo y póngase en contacto con algún médico o especialista médico online para eliminar el riesgo de consecuencias graves:

Rare

  • Blistering, peeling, or loosening of the skin
  • change in consciousness
  • chest discomfort
  • continuing vomiting
  • cracks in the skin
  • diarrhea
  • dizziness, faintness, or lightheadedness when suddenly getting up from a lying or sitting position
  • drowsiness
  • fever with or without chills
  • flushed, dry skin
  • fruit-like breath odor
  • general body swelling
  • general feeling of illness
  • high fever
  • hives
  • increased hunger
  • irregular, fast or slow, or shallow breathing
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • leg pain
  • loss of consciousness
  • loss of heat from the body
  • no blood pressure
  • no breathing
  • no pulse
  • nosebleeds
  • painful glands
  • pain or discomfort in the arms, jaw, back, or neck
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pale or blue lips, fingernails, or skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • racing heartbeat or pulse
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • red, swollen skin
  • redness or soreness of the skin
  • scaly skin
  • seeing, hearing, or feeling things that are not there
  • seizures
  • severe headache
  • sneezing
  • sores, welting, or blisters
  • stiff neck or back
  • sweating
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • unexplained weight loss
  • Appetite changes
  • burning, dry, or itching eyes
  • change in hearing
  • discharge, excessive tearing
  • redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

More Common

  • Bloody urine
  • bloody, black, or tarry stools
  • decreased frequency or amount of urine
  • heartburn
  • increased bleeding time
  • increased blood pressure
  • increased thirst
  • indigestion
  • itching skin
  • loss of appetite
  • lower back or side pain
  • nausea
  • pale skin
  • rashes
  • severe abdominal pain, cramping, or burning
  • stomach bloating
  • swelling of the face, fingers, feet, or lower legs
  • trouble breathing with or without exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting
  • vomiting of material that looks like coffee grounds, severe and continuing
  • weight gain
  • weight loss
  • Continuing ringing or buzzing or other unexplained noise in the ears
  • excess air or gas in the stomach or intestines
  • feeling of fullness
  • hearing loss
  • passing gas
  • stomach discomfort

Less Common

  • Bleeding gums
  • blood in vomit
  • blurred vision
  • burning feeling in the chest or stomach
  • chest pain
  • clay-colored stools
  • cloudy urine
  • confusion
  • constipation
  • cough or hoarseness
  • dark urine
  • difficult or labored breathing
  • difficult, burning, or painful urination
  • difficulty in swallowing
  • dilated neck veins
  • dizziness
  • extreme fatigue
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • fever or chills
  • frequent urge to urinate
  • headache
  • increased volume of pale, dilute urine
  • irregular breathing
  • irregular heartbeat
  • large, flat, blue, or purplish patches in the skin
  • light-colored stools
  • lightheadedness
  • nervousness
  • noisy breathing
  • pain or burning feeling in the throat
  • pinpoint red or purple spots on the skin
  • pounding in the ears
  • rapid, slow breathing
  • redness, swelling, or soreness of the tongue
  • severe or continuing stomach pain
  • slow heartbeat
  • sore throat
  • sores, ulcers, or white spots on the lips or tongue or inside the mouth
  • stomach upset
  • swelling or inflammation of the mouth
  • swollen glands
  • tenderness in the stomach area
  • tightness in the chest
  • tremors
  • unpleasant breath odor
  • upper right stomach pain
  • yellow eyes and skin
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • discouragement
  • dry mouth
  • fear
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • hair loss, thinning of the hair
  • increased sensitivity of the skin to sunlight
  • irritability
  • lack of appetite
  • lack of interest or pleasure
  • lack or loss of strength
  • redness or other discoloration of the skin
  • sensation of spinning
  • severe sunburn
  • sleepiness
  • trouble concentrating
  • trouble sleeping
Type Small Molecule
Accession Number DB00784  (APRD00730)
Groups Approved
Synonyms
  • Acide méfénamique
  • Acido mefenamico
  • Acidum mefenamicum
  • CN 35355
  • INF 3355
  • Mefenaminsaeure
  • Mefenaminsäure
  • N-(2,3-Xylyl)-2-aminobenzoic acid
  • N-2,3-Xylylanthranilic acid
UNII 367589PJ2C
CAS number 61-68-7
Weight Average: 241.2851
Monoisotopic: 241.110278729
Chemical Formula C15H15NO2
InChI
InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
IUPAC Name
2-[(2,3-dimethylphenyl)amino]benzoic acid
Protein binding

90%

Toxicity

Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.

Half life

2 hours

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